Akainu is one of the three Marine Admirals. His Devil fruit power allows him to turn into magma and use it in his attacks. After the timeskip, he becomes Fleet-Admiral after barely defeating Aokiji in a 10 day life or death duel against him. He is a strong believer in Absolute Justice.
Arlong is the pirate captain of all the fishman crew, the Arlong Pirates, a former member of the Sun Pirates, and the older brother of Madame Shirley. Arlong was the main reason for Nami's hatred of pirates and was the source of her suffering.
Bartholomew Kuma is a member of the shichibukai in the popular manga and anime series, One Piece. He is later revealed to be a commanding officer in the Revolutionary Army. He is the user of the Nikyu Nikyu no Mi.
Blackbeard is the captain of the Blackbeard Pirates. He was formerly a member of the Whitebeard Pirates' second division led by Portgas D. Ace, up until he killed fourth division commander Thatch for the Yami Yami no Mi, and defected from the crew. His real name is Marshall D. Teach, like most D's, he believes in fate and his character is based heavily on the real-life Blackbeard.
Buggy the Clown is the captain of the Buggy Pirates, and a former apprentice of the Roger Pirates. His Devil fruit power allows him to separate his body and control them. He became Shichibukai during the timeskip.
Big Mom's second-eldest son and one of the Sweet Commanders
One of the three Sweet Commanders of the Big Mom Pirates and the 14th daughter of Big Mom.
Crocodile was the president of the secret criminal organization, Baroque Works. He is the longest running primary villain of the series as well as the first villain to hand Luffy a complete and utter defeat. He ate the logia-type devil fruit the Suna Suna no Mi (Sand Sand fruit). He once suffered a defeat by Whitebeard and is also acquainted with Emporio Ivankov. His codename in baroque works is Mr. 0 and his partner is Miss All Sunday also known as Nico Robin. He was one of the seven warlords of the sea.
Don Krieg was the captain of the Krieg Pirates and a famous pirate of East Blue.
Enel is the main antagonist of the Skypiea Arc. He is the former "god" of Skypiea. He possesses the devil fruit known as the Goro-Goro no Mi (Rumble-Rumble Fruit), because of this, Enel believes he is invincible and develops a god-like complex.
Fujitora is a marine admiral in the One Piece series. He ate a gravity-based devil fruit. He represents blind justice. His real name is Isshou.
Gildo Tesoro is the villain of One Piece Film: Gold.
Jesus Burgess is a luchador-inspired pirate who is the helmsman and first ship captain of the Blackbeard Pirates. He is named after the real-life pirate Samuel Burgess.
Kaido is one of the four emperors and the captain of the Hundred Beasts Pirates. He currently lives in the closed off country of Wano.
Rob Lucci is one of the main antagonists of the CP9 Saga. Introduced as one of the five foremen of Galley-La Company's Dock One. He was later revealed to be the strongest member of the CP9 operating undercover to obtain the Pluton blueprint from Iceburg. After the timeskip, he is now a member of CP-0.
Smoker is a Marine Commodore which has made it his mission to capture Luffy. After the timeskip, he was promoted to Vice-Admiral. He possesses the Moku Moku no Mi (Smoke-Smoke Fruit). His jitte weapon is tipped with sea prism stone.
This One piece character was the former ruler of the Drum Empire. He ate the Munch Munch fruit, which lets him eat just about everything and takes on the properties of whatever he eats.
Zephyr is the antagonist of the movie One Piece Film: Z